PROJECT

Scientific Activity

Objectives

DENANA will deliver basic knowledge with regard to:

1. Variation of the characteristics of produced particles in order to obtain particles optimized for application but with low toxicity
   
   
2. Assessment of eco-toxicological impact and toxic mechanisms from molecular, cellular, metabolic and eco-physiological and eco-systemic measures
   
   
3. Environmental effects on the ENPs behaviour (e. g. aggregation, solubility, transport, stability and reactivity)
   
   
4. Direct determination of the molecular corona in the aqueous media for the bridging of human- and eco-toxicological effects
   
   
5. Detection, transport and modeling of exposition, mass flow of ENPs in real media
   
   
6. Long-term effects of selected ENPs on aquatic and terrestrial organisms and complex environmental systems (e.g. system of soil and plant)
   
   
7. Identification of early warning indicators of the long-term hazard potential to predict the long-term risk of the ENPs
   
   
8. Deduction of criteria for an optimized design of ENPs
   
   

 

WP H: PRODUCTION
•  Production of various ENPs of different coating and/or charge and subsequent characterisation

WP A: APPLICATION
•  Disposal of SiO₂NP i into lubrication-oil, characterisation and technical check

WP K: COORDINATION
•  Coordination of the consortium
•  Development of design criteria
•  Comparison and assessment of short- and long-term test results
•  Comparison and assessment with OECD requirements

WP E: EXPOSITION
•  Analysis of the market and potential applications
•  Life cycle analysis and dispersion- and transport modeling
•  Identification of the risk profile

WP V: FATE
•  Detection of ENPs in different environmental media
•  Modelling of interaction and transport in environmental media
•  Medium- and long-term stability of ENPs in soil
•  Quantification of selected ENPs in organisms

WP U1: WATERS
•  Characterisation and stability of ENPs in aqueous medium
•  Transport of ENPs in sandy sediments
•  Aquatic test systems
•  Agglomeration of ENPs and dissolved organic matter

WP U2: SOIL
•  Characterisation and stability of ENPs in soil
•  Transport of ENPs in soil
•  Terrestrial test systems

WP L: LONG-TERM EFFECTS
•  Installation, maintenance and periodic sampling in long-term test systems
•  Identification of early warning indicators and ROS –formation of ENPs
•  Performance of long- and short-term eco- toxicity test systems

 

Relation of workpackages to DENANA-objectives       
     

The chart below depicts the network of the WPs and the members of the consortium.